No. 10: Raiders over Eagles (2009) – OAK +14
The Raiders upset the eventual 11-5 Eagles with Jamarcus Russell under center. Kyle Terada-USA TODAY Sports
No. 9: Vikings over Eagles (2010) – MIN +14
With WR Joe Webb under center, the Vikings defeated the Eagles 24-14 after 224 total yards…
With WR Joe Webb under center, the Vikings defeated the Eagles 24-14 after 224 total yards from Percy Harvin and Adrian Peterson. Howard Smith-USA TODAY Sports
No. 8: Jaguars over Broncos (1996 playoffs) – Jaguars +14
After going 13-3, the Broncos fell to the Jaguars in their second year of their existence…
After going 13-3, the Broncos fell to the Jaguars in their second year of their existence in the 1996 playoffs.
No. 7: Giants over Broncos (2017) – NYG +14
After an 0-5 start, the Giants defeated the Broncos 23-10 despite just 11 completions by Eli…
After an 0-5 start, the Giants defeated the Broncos 23-10 despite just 11 completions by Eli Manning. Isaiah J. Downing-USA TODAY Sports
No. 6: Browns over Steelers (1999) – CLE +14.5
In their return to Cleveland, the Browns defeated the Steelers in Week 10 of 1999 despite…
In their return to Cleveland, the Browns defeated the Steelers in Week 10 of 1999 despite being 14.5 underdogs. Jamie Squire /Allsport
No. 5: Raiders over Steelers (2009) – OAK +14.5
Bruce Gradkowski threw for 308 yards and 3 TDs in Pittsburgh to defeat the 6-2 Steelers.…
Bruce Gradkowski threw for 308 yards and 3 TDs in Pittsburgh to defeat the 6-2 Steelers. Jason Bridge-USA TODAY Sports
No. 4: Bills over Vikings (2018) – BUF +16.5
After being blown out in the first two weeks of the season, the Bills bounced back…
After being blown out in the first two weeks of the season, the Bills bounced back with a 27-6 victory over the Vikings despite being 16.5 point underdogs. Brace Hemmelgarn-USA TODAY Sports
No. 3: Washington over Cowboys (1995) – WAS +17.5
The Cowboys were 10-2 in 1995, but fell to Washington 24-17 in an NFC East matchup.…
The Cowboys were 10-2 in 1995, but fell to Washington 24-17 in an NFC East matchup. Dallas would still go on to win the Super Bowl despite this huge upset. Joe Patronite/ALLSPORT
No. 2: Jets over Rams (2020) – NYJ +17.5
The 0-13 Jets defeated the Rams in Week 15 of 2020 to earn their first win…
The 0-13 Jets defeated the Rams in Week 15 of 2020 to earn their first win of the season. Robert Hanashiro-USA TODAY Sports
No. 1 – Patriots over Rams (2002) – NE +14
This isn’t the biggest betting spread upset, but it is the most important as the Patriots…
This isn’t the biggest betting spread upset, but it is the most important as the Patriots defeated the Rams in Super Bowl XXXVI to kick off their dynasty. Mandatory Credit: USA TODAY Sports
