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Chicago White Sox at Los Angeles Angels odds, picks and prediction

The Chicago White Sox (0-1) and Los Angeles Angels (1-0) meet in the second game of their four-game set Friday evening at 9:38 p.m. ET at Angel Stadium. Let’s analyze BetMGM Sportsbook‘s lines around the White Sox vs. Angels odds with MLB picks and predictions.

LHP Dallas Keuchel is the projected starter for the White Sox. He was 6-2 with a fantastic 1.99 ERA, a 1.09 WHIP, 6.0 K/9 and 2.4 BB/9 in 63 1/3 IP over 11 starts last season. He did a great job of limiting hard contact, but was also pretty lucky, with a .255 BABIP and a 5% home run per fly ball rate. He has posted a 3.26 ERA and 6.4 K/9 in 12 starts at Angel Stadium.

LHP Andrew Heaney is the projected starting pitcher for the Angels. He made 12 starts in 2020 and went 4-3 with a 4.46 ERA, 1.23 WHIP, 9.5 K/9 and 2.6 BB/9 in 66 2/3 IP. In five starts at Angel Stadium, he put up a 2.81 ERA and 10.1 K/9, bringing his career marks at the venue to 3.84 and 9.1, respectively.

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White Sox at Angels odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 11:30 a.m. ET.

  • Money line: White Sox +105 (bet $100 to win $105) | Angels -130 (bet $130 to win $100)
  • Against the spread/ATS: White Sox +1.5 (-185) | Angels -1.5 (+150)
  • Over/Under: 8.5 (O: -110 | U: -110)

Prediction

White Sox 5, Angels 4

Money line (ML)

Even without OF Eloy Jimenez (pectoral) in the lineup, the White Sox have plenty of bats that can do damage. They led the league in 2020 with a 142 wRC+ and .238 ISO vs left-handed pitching, while ranking 2nd in OPS.

Given Heaney’s fly ball lean and history of being prone to the long ball (career 1.5 HR/9), the WHITE SOX (+105) are a good bet to come out on top in this one.

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Run line/Against the spread (ATS)

This sets up to be a close game involving two pretty evenly matched starting pitchers.

Laying nearly 2 to 1 odds to get +1.5 runs with the White Sox doesn’t seem like a wise play; however, flipping to WHITE SOX -1.5 (+165) on the alternate line looks more appealing. It wouldn’t be surprising for them to touch up Heaney for a couple of home runs.

Over/Under (O/U)

Both pitchers in this matchup are solid, though neither really profiles as a front-line starter. The Over is 12-4-3 in the White Sox’s last 19 road games against a left-handed starter and 3-1-1 in the Angels’ previous five contests against a lefty.

The offenses should be able to push enough runs across for the OVER 8.5 (-110) to cash again.

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